Season 10 (2025)

Award-winning artist Sheryl Crow hosts and performs in this telecast, along with remarks by SU2C co-founder Katie Couric. The telecast will feature performances by Jonas Brothers, Noah Cyrus, Gavin DeGraw, Marcus King, Brothers Osborne, Jon Pardi, Jelly Roll, Dan + Shay and CeCe Winans — joined by Nashville Community Gospel Choir, all lending their talents to help raise critical funds for cancer research. The special will also include pre-taped segments featuring Kevin Bacon, Jamie Foxx, Tim McGraw, Zoe Saldaña, Keith Urban, and Reese Witherspoon. Grammy®. Music icon Dolly Parton previously participated in a tune-in campaign to raise awareness for the Nashville telecast.